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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERO1L
All Species:
36.36
Human Site:
T405
Identified Species:
50
UniProt:
Q96HE7
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HE7
NP_055399.1
468
54393
T405
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Chimpanzee
Pan troglodytes
XP_509950
468
54427
T405
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Rhesus Macaque
Macaca mulatta
XP_001103965
468
54383
T405
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Dog
Lupus familis
XP_547813
468
54343
I405
R
L
W
G
K
L
Q
I
Q
G
L
G
T
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R180
464
54066
T401
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Rat
Rattus norvegicus
Q8R4A1
464
54000
T401
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515503
465
53870
T402
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Chicken
Gallus gallus
XP_421473
463
52908
T400
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Frog
Xenopus laevis
Q6DD71
465
53720
T403
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Zebra Danio
Brachydanio rerio
Q7T3D1
489
56571
T396
R
L
W
G
K
L
Q
T
Q
G
L
G
T
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A6
483
55641
L423
T
Q
G
L
G
T
A
L
K
I
L
Y
S
E
K
Honey Bee
Apis mellifera
XP_623933
471
55049
G411
W
G
K
L
Q
I
H
G
L
G
T
A
L
K
I
Nematode Worm
Caenorhab. elegans
Q7YTU4
478
55136
V396
K
C
R
L
W
G
K
V
Q
T
H
G
M
G
T
Sea Urchin
Strong. purpuratus
XP_796844
897
101920
I829
K
L
W
G
K
L
Q
I
K
G
L
G
T
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C7S7
469
53812
Q412
G
D
Q
T
L
Q
L
Q
R
N
E
V
I
A
L
Baker's Yeast
Sacchar. cerevisiae
Q03103
563
65014
K499
G
T
V
N
K
W
K
K
A
W
N
T
E
V
N
Red Bread Mold
Neurospora crassa
Q7SEY9
668
75589
G429
W
G
K
L
Q
T
A
G
Y
G
T
A
L
K
V
Conservation
Percent
Protein Identity:
100
99.5
98.7
96.3
N.A.
91.8
91.4
N.A.
84.6
77.7
70.9
62.1
N.A.
46.1
48.4
41.4
29.3
Protein Similarity:
100
99.5
99.3
97.8
N.A.
95.9
95.7
N.A.
90.1
85.4
83.9
75.4
N.A.
64.1
65.6
60.8
37.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
6.6
6.6
13.3
80
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
100
100
N.A.
20
26.6
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
22.5
22.1
Protein Similarity:
N.A.
N.A.
N.A.
55.6
41.2
38
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
6
0
0
12
0
71
0
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
6
0
6
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
12
6
65
6
6
0
12
0
77
0
71
0
6
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
6
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
0
12
0
6
0
0
6
0
6
% I
% Lys:
12
0
12
0
71
0
12
6
12
0
0
0
0
12
6
% K
% Leu:
0
65
0
24
6
65
6
6
6
0
71
0
12
0
71
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
6
0
0
0
0
0
6
6
0
0
0
6
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
6
6
0
12
6
65
6
65
0
0
0
0
0
0
% Q
% Arg:
59
0
6
0
0
0
0
0
6
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% S
% Thr:
6
6
0
6
0
12
0
53
0
6
12
6
65
0
6
% T
% Val:
0
0
6
0
0
0
0
6
0
0
0
6
0
6
6
% V
% Trp:
12
0
65
0
6
6
0
0
0
6
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
6
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _